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Toward Defining the Course of Evolution: Minimum Change for a Specific Tree Topology
Walter M. Fitch
Vol. 20, No. 4 (Dec., 1971), pp. 406-416
Stable URL: http://www.jstor.org/stable/2412116
Page Count: 11
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A method is presented that is asserted to provide all hypothetical ancestral character states that are consistent with describing the descent of the present-day character states in a minimum number of changes of state using a predetermined phylogenetic relationship among the taxa represented. The character states used as examples are the four messenger RNA nucleotides encoding the amino acid sequences of proteins, but the method is general.
Systematic Zoology © 1971 Oxford University Press