You are not currently logged in.
Access your personal account or get JSTOR access through your library or other institution:
If You Use a Screen ReaderThis content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Confidence Interval about the Response at the Stationary Point of a Response Surface, with an Application to Preclinical Cancer Therapy
Walter H. Carter, Jr., Vernon M. Chinchilli, Eleanor D. Campbell and Galen L. Wapler
Vol. 40, No. 4 (Dec., 1984), pp. 1125-1130
Published by: International Biometric Society
Stable URL: http://www.jstor.org/stable/2531164
Page Count: 6
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Preview not available
A method of calculating a confidence interval about the response at the stationary point of a response surface is presented. We show that the technique can also be used to calculate a confidence region about the location of the stationary point. The procedure is applied, via Cox's proportional-hazards model, to the analysis of survival data from a preclinical cancer chemotherapy experiment involving the combination of two drugs. It is seen that the results can be useful in determining the existence of a therapeutic synergism.
Biometrics © 1984 International Biometric Society