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Analysis of In-situ Hybridization Data for Unique Genes Using GLIM

David J. Scott and Andrew H. Sinclair
Biometrics
Vol. 45, No. 2 (Jun., 1989), pp. 601-604
DOI: 10.2307/2531500
Stable URL: http://www.jstor.org/stable/2531500
Page Count: 4
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Analysis of In-situ Hybridization Data for Unique Genes Using GLIM
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Abstract

When a radioactively-labelled gene probe is hybridized to chromosomes on a microscope slide, the site of hybridization should be revealed by counting emitted β-particles on a photographic overlay. However, in some cases background radiation disguises the site of hybridization. Using GLIM to fit Poisson regression models, it is possible to determine the chromosome to which the gene has hybridized.

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