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Recurrent Oral Ulceration Treated With Mysteclin: A Controlled Study

A. M. Denman and A. A. Schiff
The British Medical Journal
Vol. 1, No. 6173 (May 12, 1979), pp. 1248-1249
Published by: BMJ
Stable URL: http://www.jstor.org/stable/25432337
Page Count: 2
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Abstract

Twenty patients with recurrent oral ulceration participated in a placebo-controlled, double-blind trial of Mysteclin syrup (tetracycline hydrochloride and amphotericin) used as a mouthwash. Though a small, consistent improvement occurred with placebo, there was a significant reduction in mean pair scores and numbers of new ulcers recorded daily during the active-treatment periods, the effect lasting for at least four weeks after treatment was stopped. In contrast to topical steroid preparations, Mysteclin syrup is efficacious when begun at any stage of the disorder and is not associated with adverse systemic effects.

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