Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

Treatment of Infectious Mastitis during Lactation: Antibiotics versus Oral Administration of Lactobacilli Isolated from Breast Milk

Rebeca Arroyo, Virginia Martín, Antonio Maldonado, Esther Jiménez, Leónides Fernández and Juan Miguel Rodríguez
Clinical Infectious Diseases
Vol. 50, No. 12 (15 June 2010), pp. 1551-1558
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/25679916
Page Count: 8
  • Download ($42.00)
  • Subscribe ($19.50)
  • Cite this Item
Treatment of Infectious Mastitis during Lactation: Antibiotics versus Oral Administration of Lactobacilli Isolated from Breast Milk
Preview not available

Abstract

Background. Mastitis is a common infectious disease during lactation, and the main etiological agents are staphylococci, streptococci, and/or corynebacteria. The efficacy of oral administration of Lactobacillus fermentum CECT5716 or Lactobacillus salivarius CECT5713, two lactobacilli strains isolated from breast milk, to treat lactational mastitis was evaluated and was compared with the efficacy of antibiotic therapy. Methods. In this study, 352 women with infectious mastitis were randomly assigned to 3 groups. Women in groups A (n = 124) and B (n = 127) ingested daily 9 log₁₀ colony-forming units (CFU) of L. fermentum CECT5716 or L. salivarius CECT5713, respectively, for 3 weeks, whereas those in group C (n = 101) received the antibiotic therapy prescribed in their respective primary care centers. Results. On day 0, the mean bacterial counts in milk samples of the 3 groups were similar (4.35–4.47 log₁₀ CFU/mL), and lactobacilli could not be detected. On day 21, the mean bacterial counts in the probiotic groups (2.61 and 2.33 log₁₀ CFU/mL) were lower than that of the control group (3.28 log₁₀ CFU/mL). L. fermentum CECT5716 and L. salivarius CECT5713 were isolated from the milk samples of women in the probiotic groups A and B, respectively. Women assigned to the probiotic groups improved more and had lower recurrence of mastitis than those assigned to the antibiotic group. Conclusions. The use of L. fermentum CECT5716 or L. salivarius CECT5713 appears to be an efficient alternative to the use of commonly prescribed antibiotics for the treatment of infectious mastitis during lactation. ClinicalTrials.gov identifier. NCT00716183.

Page Thumbnails

  • Thumbnail: Page 
1551
    1551
  • Thumbnail: Page 
1552
    1552
  • Thumbnail: Page 
1553
    1553
  • Thumbnail: Page 
1554
    1554
  • Thumbnail: Page 
1555
    1555
  • Thumbnail: Page 
1556
    1556
  • Thumbnail: Page 
1557
    1557
  • Thumbnail: Page 
1558
    1558