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Antiserum to Lens Antigens Immunostains Müller Glia Cells in the Neural Retina

A. A. Moscona, Lyle Fox, Jenie Smith and Linda Degenstein
Proceedings of the National Academy of Sciences of the United States of America
Vol. 82, No. 16 (Aug. 15, 1985), pp. 5570-5573
Stable URL: http://www.jstor.org/stable/25693
Page Count: 4
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Abstract

Antiserum to a lens fraction enriched for α -crystallin selectively immunostains Muller glia cells in the neural retina of several vertebrate species. Also, in embryonic retina (chicken), this antiserum reacts with Muller cells and, at early stages of development, with their apparent precursors. Thus, antibodies to a lens product(s) detect a Muller glia cell marker that begins to be expressed very early in their ontogeny and can be useful in studies on differentiation, function, and pathologies of this cell type.

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