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EASILY MISSED? Carcinoid syndrome

R Srirajaskanthan, D Shanmugabavan and J K Ramage
BMJ: British Medical Journal
Vol. 341, No. 7773 (18 September 2010), pp. 603-604
Published by: BMJ
Stable URL: http://www.jstor.org/stable/25738185
Page Count: 2
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Abstract

KEY POINTS Carcinoid syndrome results from kinins and serotonin released from neuroendocrine tumours, most commonly those in the gastrointestinal tract. Its most common symptoms are facial flushing, diarrhoea, and cramping abdominal pain Delayed diagnosis may lead to progression of disease and consequently shorter survival from time of diagnosis Urinary 5-HIAA and abdominal ultrasound are initial investigations in primary care; foods containing tyramine should be excluded at least 24 hours before urine collection Carcinoid syndrome can be treated with somatostain analogues or interferon alfa, or both. Surgery is the only option with curative potential for neuroendocrine tumours

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