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Morphine and Other Opiates from Beef Brain and Adrenal

Avram Goldstein, Ronald W. Barrett, Iain F. James, Louise I. Lowney, Charles J. Weitz, Laura L. Knipmeyer and Henry Rapoport
Proceedings of the National Academy of Sciences of the United States of America
Vol. 82, No. 15 (Aug. 1, 1985), pp. 5203-5207
Stable URL: http://www.jstor.org/stable/25919
Page Count: 5
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Morphine and Other Opiates from Beef Brain and Adrenal
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Abstract

We describe nonpeptide opioids found in extracts of beef hypothalamus and adrenal, which are recognized by antisera raised against morphine. Four have been purified to homogeneity. One is morphine. The structures of the other three have not been determined yet. None of them are derived from morphine or normorphine after extraction from the tissues. It is not known whether the opiates described here are of endogenous or exogenous origin.

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