Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Expression of the Cytokeratin Endo A Gene during Early Mouse Embryogenesis

Philippe Duprey, Dominique Morello, Marc Vasseur, Charles Babinet, Hubert Condamine, Philippe Brulet and Francois Jacob
Proceedings of the National Academy of Sciences of the United States of America
Vol. 82, No. 24 (Dec. 15, 1985), pp. 8535-8539
Stable URL: http://www.jstor.org/stable/26624
Page Count: 5
  • Read Online (Free)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Expression of the Cytokeratin Endo A Gene during Early Mouse Embryogenesis
Preview not available

Abstract

Expression of cytokeratin endo A has been analyzed during mouse blastocyst formation and embryonal carcinoma cell differentiation. To study the regulation of endo A expression, nuclease S1 mapping experiments have been performed on RNA extracted from two-cell to 7.5-day embryos. Low levels of endo A mRNA begin to be detectable in eight-cell embryos. The amount of this mRNA increases at the blastocyst stage, suggesting that endo A expression is regulated at the mRNA level during blastocyst formation. At this stage, in situ hybridization studies show that endo A mRNA is present in the trophectoderm but not in the inner cell mass. In 7.5-day embryos, endo A mRNAs are also detectable in the endoderm layer and in the amnion.

Page Thumbnails

  • Thumbnail: Page 
8535
    8535
  • Thumbnail: Page 
8536
    8536
  • Thumbnail: Page 
8537
    8537
  • Thumbnail: Page 
8538
    8538
  • Thumbnail: Page 
8539
    8539