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Allergic Contact Dermatitis Due to Urethane Acrylate in Ultraviolet Cured Inks

J. R. Nethercott, H. R. Jakubovic, C. Pilger and J. W. Smith
British Journal of Industrial Medicine
Vol. 40, No. 3 (Aug., 1983), pp. 241-250
Published by: BMJ
Stable URL: http://www.jstor.org/stable/27723717
Page Count: 10
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Allergic Contact Dermatitis Due to Urethane Acrylate in Ultraviolet Cured Inks
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Abstract

Seven workers exposed to ultraviolet printing inks developed contact dermatitis. Six cases were allergic and one irritant. A urethane acrylate resin accounted for five cases of sensitisation, one of which was also sensitive to pentaerythritol triacrylate and another also to an epoxy acrylate resin. One instance of allergy to trimethylpropane triacrylate accounted for the sixth case of contact dermatitis in this group of workers. An irritant reaction is presued to account for the dematitis in the individual not proved to have cutaneous allergy by patch tests. In this instance trimethylpropane triacrylate was thought to be the most likely irritating agent. Laboratory investigation proved urethane acrylate to be an allergen. The results of investigations of the sensitisation potentials of urethane acrylate, methylmethacrylate, epoxy acrylate resins, toluene-2,4-diisocyanate, and other multifunctional acrylic monomers in the albino guinea pig are presented. The interpretation of such predictive tests is discussed.

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