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Hours of Work and the Risk of Developing Impaired Fasting Glucose or Type 2 Diabetes Mellitus in Japanese Male Office Workers
N. Nakanishi, K. Nishina, H. Yoshida, Y. Matsuo, K. Nagano, K. Nakamura, K. Suzuki and K. Tatara
Occupational and Environmental Medicine
Vol. 58, No. 9 (Sep., 2001), pp. 569-574
Published by: BMJ
Stable URL: http://www.jstor.org/stable/27731551
Page Count: 6
You can always find the topics here!Topics: Type 2 diabetes mellitus, Overtime, Disease risks, Fasting, Cigarette smoking, Blood plasma, Alcohols, Support personnel, Exercise, Diabetes mellitus
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Objective—To investigate the association between duration of overtime and the development of impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM). Methods—A cohort of 1266 Japanese male office workers aged 35–59 years and free of IFG (fasting plasma glucose concentration 6.1–6.9 mmol/l), type 2 DM (fasting plasma glucose concentration of 7.0 mmol/l or more or taking hypoglycaemic medication), history of diabetes, or medication for hypertension were re-examined over 5 successive years after their initial examinations in 1994. Results—138 men developed IFG or type 2 DM during the 5736 person-years of follow up. After controlling for potential predictors of diabetes, the relative risks of IFG or type 2 DM, compared with those who worked <8.0 hours a day, were 0.82 (95% confidence interval (95% CI) 0.54 to 1.26), 0.69 (95% CI 0.38 to 1.26), 0.63 (95% CI: 0.37 to 1.09), and 0.50 (95% CI: 0.25 to 0.98) for those who worked 8.0–8.9, 9.0–9.9, 10.0–10.9, and of 11.0 hours or more a day, respectively (p for trend=0.020). 87 and 54 men developed IFG and type 2 DM during the 5817 and 5937 person-years of follow up, respectively. The multivariate adjusted relative risks of IFG tended to decrease with an increase in hours of overtime work a day, but did not reach significance (p for trend=0.202). On the other hand, the multivariate adjusted relative risks of type 2 DM significantly decreased with an increase in hours of overtime work a day (p for trend=0.014). Conclusion—Longer overtime is a negative risk factor for the development of IFG or type 2 DM in Japanese male office workers.
Occupational and Environmental Medicine © 2001 BMJ