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Time Sequences for Differentiation in Cellular Slime Molds

David Francis
The Quarterly Review of Biology
Vol. 44, No. 3 (Sep., 1969), pp. 277-290
Stable URL: http://www.jstor.org/stable/2820210
Page Count: 14
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Time Sequences for Differentiation in Cellular Slime Molds
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Abstract

A critical discussion of developmental processes in the cellular slime molds is presented. The concept of timing sequence, consisting of a set of gene-product units (GPUs) linked by interactions, is proposed to describe significant changes during development of any organism. It is shown how the contrasting outlooks and experimental approaches of the two major laboratories involved in biochemical work on slime molds may be brought together under this framework. Three timing sequences which may be applicable to the particular case of cellular slime molds are presented and discussed in detail. Attention is called to experiments which will most rapidly reveal the actual timing sequence.

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