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HIV-1 infection and Fertility in Dar es Salaam, Tanzania / Infection du VIH-1 et fécondité à Dar es Salaam, Tanzanie

Gilda Sedgh, Ulla Larsen, D. Spiegelman, Genard Msamanga and Wafaie W. Fawzi
African Journal of Reproductive Health / La Revue Africaine de la Santé Reproductive
Vol. 10, No. 3 (Dec., 2006), pp. 41-52
DOI: 10.2307/30032470
Stable URL: http://www.jstor.org/stable/30032470
Page Count: 12
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
HIV-1 infection and Fertility in Dar es Salaam, Tanzania / Infection du VIH-1 et fécondité à Dar es Salaam, Tanzanie
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Abstract

The objective of this study was to examine the association of HIV-1 infection with rates of pregnancy and pregnancy loss in Dar es Salaam, Tanzania. A retrospective cohort study of 1,006 HIV-infected women and 485 uninfected women was employed. In multivariate analyses controlling for other predictors of pregnancy, the association of HIV-seropositivity with a woman's reported number of pregnancies was of borderline significance (RR =1.13,95% CI = 1.00,1.27). HIV infection was not associated with pregnancy loss in multivariate analysis. The adjusted pregnancy rate ratio comparing HIV-positive women at the earliest stages of infection to all uninfected women was 1.22 (95% CI = 1.04,1.42). HIV infection was not associated with female fertility when comparing women in the most advanced stages of infection to all uninfected women. We conclude that HIV-1 infected women had higher pregnancy rates than uninfected women. This association disappeared when analyses were limited to women with advanced disease. /// Le but de cette étude est d'examiner l'association de l'infection du VIH-1 à la fréquence grossesse et la perte de grossesse à Dar es Salaam, Tanzanie. Une étude cohorte retrospective de 1,006 femmes infectées du VIH-l et 485 femmes qui l'étaient pas a été menée. Une analyse multifactorielle pour déterminer les indices de grossesse, l'association de la séropositive - VIH avec le nombre de grossesses signalées était très peu significative (RR = 1,13,1,13,95% CI = 100,1,27). La séropositivité n'a pas été associée à la perte de grossesse dans l'analyse multifactorielle. La proportion de taux de grossesse si l'on compare les femmes séropositives, tout au debut de l'infection, aux femmes qui ne sont pas atteintes, était 1,22 avec la stérilité chez la femme si l'on compare les femmes non-atteintes. Nous concluons que les femmes séropositives ont des taux de grossesse plus élèves que les femmes non-atteintes. Cette association a disparu quand les analyses ont été limitées aux femmes chez qui la maladie est avancée.

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