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Journal Article

Complement Fixation in Typhoid Fever

L. G. Hadjopoulos
The Journal of Infectious Diseases
Vol. 31, No. 3 (Sep., 1922), pp. 226-232
Published by: Oxford University Press
Stable URL:
Page Count: 7

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Topics: Blood, Typhoid, Typhoid fever, Agglutination, Antigens, Reading tables, Hemolysis, Numerals, Cultural values
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In the course of typhoid infection, the formation of complement-fixing antibodies is one of the earliest and most constant immune manifestations. The introduction of a different quantitative, active serum technic for the complement-fixation test makes it possible to utilize this property for the diagnosis of typhoid fever, with satisfactory results. In a limited number of typhoid cases the test has been repeated with inactive serum and found similarly satisfactory. It is recommended, however, that the active serum technic be used, as it saves much time in the routine work of the test.

Notes and References

This item contains 5 references.

  • 1
    Ann. de l'Inst. Pasteur, 1901, 3, p. 289.
  • 2
    Phys. et Path. Gèn., 1912, 14, p. 86.
  • 3
    Jour. Med. Research, 1912, 21, p. 373.
  • 5
    Am. Jour. Med. Sc, 1907, 133, p. 896.
  • 6
    Path. Microorganisms, 1917, p. 345.