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Soluble Toxic Products of the Enteritidis Paratyphoid B Group and Their Action Especially in Relation to Blood Sugar
Maud L. Menten
The Journal of Infectious Diseases
Vol. 38, No. 4 (Apr., 1926), pp. 354-365
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30083255
Page Count: 12
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Soluble toxic substances derived from organisms of the enteritidisparatyphoid B group produce alterations in the blood sugar and morphologic lesions which are identical with those produced by injection of the living or killed bacteria. On intravenous injection of the toxic substances a series of blood sugar curves are obtained which are proportional to the amount of the substance injected. The characteristics of these curves, which have been divided into three groups, are discussed. A second injection after an interval of less than two weeks causes modifications of the hyperglycemic and hypoglycemic curves obtained with a single injection. The toxic substance is thermostabile, soluble in water and can be precipitated by alcohol and concentrated acetic acid.
The Journal of Infectious Diseases © 1926 Oxford University Press