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Lack of Association between Infection with a Novel Human Coronavirus (HCoV), HCoV-NH, and Kawasaki Disease in Taiwan
Luan-Yin Chang, Bor-Luen Chiang, Chuan-Liang Kao, Mei-Hwan Wu, Pei-Jer Chen, Ben Berkhout, Hui-Ching Yang, Li-Min Huang and Kawasaki Disease Research Group
The Journal of Infectious Diseases
Vol. 193, No. 2 (Jan. 15, 2006), pp. 283-286
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30086472
Page Count: 4
You can always find the topics here!Topics: Mucocutaneous lymph node syndrome, Infections, RNA, Reverse transcriptase polymerase chain reaction, Human coronavirus NL63, Diameters, Throat, Polymerase chain reaction, Coronavirus, Children
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We investigated whether infection with a novel human coronavirus (HCoV), called New Haven coronavirus (HCoVNH): which is similar to and likely represents the same species as another novel HCoV, HCoV-NL63:is associated with Kawasaki disease (KD) in Taiwan. Fifty-three patients with KD were enrolled in our study. Serum, peripheral-blood mononuclear cells, nasopharyngeal aspirates, throat swabs, and rectal swabs from these patients were assayed for HCoVNL63 by real-time reverse-transcriptase (RT) polymerase chain reaction (PCR), and the throat swabs, nasopharyngeal aspirates, and rectal swabs were also assayed for HCoV-NH by RT-PCR. All PCR results were negative for both HCoV-NL63 and HCoV-NH; therefore, we did not find any association between HCoV-NH infection and KD in Taiwan.
The Journal of Infectious Diseases © 2006 Oxford University Press