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The "Antiendotoxic" Action of Certain Organic Sulfur Compounds with Review of the Theories of the Mechanism of Action of the Sulfonamide Compounds

Paul Gross, Frank B. Cooper and Marion Lewis
The Journal of Infectious Diseases
Vol. 63, No. 3 (Nov. - Dec., 1938), pp. 245-250
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30088414
Page Count: 6
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The "Antiendotoxic" Action of Certain Organic Sulfur Compounds with Review of the Theories of the Mechanism of Action of the Sulfonamide Compounds
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Abstract

No antiendotoxic action of sulfanilamide could be demonstrated against formalin-killed meningococci in mice, against formalin-killed streptococci in mice, or guinea pigs, or heat-killed streptococci in guinea pigs. Similarly, no antiendotoxic action of 4,4'-di-(acetylamino)-diphenylsulfone was demonstrable against formalin-killed streptococci in mice.

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