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The "Antiendotoxic" Action of Certain Organic Sulfur Compounds with Review of the Theories of the Mechanism of Action of the Sulfonamide Compounds
Paul Gross, Frank B. Cooper and Marion Lewis
The Journal of Infectious Diseases
Vol. 63, No. 3 (Nov. - Dec., 1938), pp. 245-250
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30088414
Page Count: 6
You can always find the topics here!Topics: Sulfanilamides, Dosage, Sublethal dosage, Chemical suspensions, Endotoxins, Sulfonamides, Mice, Medical treatment, Sulfones, Organic sulfur compounds
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No antiendotoxic action of sulfanilamide could be demonstrated against formalin-killed meningococci in mice, against formalin-killed streptococci in mice, or guinea pigs, or heat-killed streptococci in guinea pigs. Similarly, no antiendotoxic action of 4,4'-di-(acetylamino)-diphenylsulfone was demonstrable against formalin-killed streptococci in mice.
The Journal of Infectious Diseases © 1938 Oxford University Press