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The Prophylactic Use of Serums and Vaccines in Acute Bacillary Dysentery

Joseph Felsen and A. G. Osofsky
The Journal of Infectious Diseases
Vol. 63, No. 3 (Nov. - Dec., 1938), pp. 298-300
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30088419
Page Count: 3
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The Prophylactic Use of Serums and Vaccines in Acute Bacillary Dysentery
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Abstract

From these observations, taking into account the limited number of experimental animals used, the following inferences can be drawn: Immune rabbit serums protected mice against ten lethal doses of a moderately virulent strain of B, dysenteriae. This protection was evinced when the protective serums were injected previously to, or together with the inoculation of the organism. When the serum injection followed the fatal dose of bacteria no protection could be observed. Active immunization produced by the use of vaccine also offered a considerable degree of protection.

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