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Common Antigens among Filarial and Other Nematode Parasites of Man
José Oliver-González and Federico Hernández Morales
The Journal of Infectious Diseases
Vol. 77, No. 2 (Sep. - Oct., 1945), pp. 92-95
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30089374
Page Count: 4
You can always find the topics here!Topics: Antigens, Microfilariae, Roundworms, Skin, Infections, Parasites, Worms, Blood, Adults, Immunology
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A total of 90 people, harboring microfilariae of Wuchereria bancrofti, were injected intradermally with various dilutions of saline extracts made from the dried and pulverized dog filariid, Dirofilaria immitis, of the rat filariid, Litmosoides carinii, and of the microfilariae of Wuchereria bancrofti. Ninety people, without microfilariae in the blood, were similarly tested. The number of positive reactions to all dilutions of the 3 filarial antigens in the individuals with microfilariae were note significantly different from those without microfilariae. A total of 36 soldiers and sailors from Continental United States, all recently transferred to Puerto Rico, negative for microfilariae and for intestinal nematodes were tested with 1:200 and 1:10,000 dilutions of the filarial antigens. Negative reactions to all antigen dilutions were observed in all but 2 cases. These 2 cases probably represent individuals sensitive to the extracting solution. The non-specificity of the test in the group of 180 Puerto Ricans may be attributed to cross reactions with other nematodes, as a high incidence of infection with intestinal parasites was encountered in this group of microfilaria-positive and negative individuals.
The Journal of Infectious Diseases © 1945 Oxford University Press