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Extracts of Normal Tissues in Experimental Tuberculosis
Richard S. Austin
The Journal of Infectious Diseases
Vol. 37, No. 3 (Sep., 1925), pp. 256-264
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30101790
Page Count: 9
You can always find the topics here!Topics: Lungs, Kidneys, Spleen, Liver, Lesions, Inoculation, Tuberculosis, Bacillus, Ungulates, Human organs
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In summary it may be stated that the inoculation of simple extracts, not incubated, of certain fresh normal organs of the rabbit appears to influence the development of experimental tuberculosis in rabbits. The extracts of different kinds of organs vary considerably as to the amount of influence displayed. Extracts of suprarenal and lung frequently would seem to retard the development of the disease, those of heart and liver produce less effect as a rule, while extracts of spleen and kidney exert little or no influence. The freshness of the organs used, the short time utilized in preparing the extracts, the avoidance of incubation and the preservation of the extracts, between inoculations, at icebox temperature make it seem possible that the more or less protective substances present in some of the organ extracts exist in the organs before removal from the animal.
The Journal of Infectious Diseases © 1925 Oxford University Press