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Hemolysin and Leukocidin Production by 80/81 Strains of Staphylococcus aureus
John A. Donahue and Jack N. Baldwin
The Journal of Infectious Diseases
Vol. 116, No. 3 (Jun., 1966), pp. 324-328
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30102093
Page Count: 5
You can always find the topics here!Topics: Toxins, Hemolysin proteins, Leukocidins, Neutrophils, Virulence, Erythrocytes, Bacteriophages, Hemolysis, Phagocytosis, Staphylococcus aureus
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No distinctive differences in the types of hemolysins or in the amount of alpha hemolysin produced were observed when cultures of the 80/81 strain of Staphylococcus aureus were compared with cultures of other distinct phage types. The only crude toxin preparations that caused complete disruption of human neutrophils, as observed on stained slides, were obtained from cultures of the 80/81 strain. The effect has been attributed to the capacity of cultures of the 80/81 strain to produce a leuko-cidin which resembles the Panton-Valentine leukocidin. It is felt that the ability to produce this substance contributes to the apparently increased virulence of the 80/81 strain.
The Journal of Infectious Diseases © 1966 Oxford University Press