You are not currently logged in.
Access your personal account or get JSTOR access through your library or other institution:
A Prospective Study of Visceral Leishmaniasis in an Endemic Area of Brazil
R. Badaró, T. C. Jones, R. Lorenço, B. J. Cerf, D. Sampaio, E. M. Carvalho, H. Rocha, R. Teixeira and W. D. Johnson Jr.
The Journal of Infectious Diseases
Vol. 154, No. 4 (Oct., 1986), pp. 639-649
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30104946
Page Count: 11
Preview not available
The epidemiology, clinical patterns, and risk factors for visceral leishmaniasis were prospectively studied in an endemic area of Brazil. The prevalence of disease was S.l^o for chil- dren <5 years of age, and the annual incidence was 4.3 cases per 1,000 children. The number of children with disease fluctuated yearly and seasonally, and distribution of the disease varied within the endemic area. Risk factors included young age (median, three years) and malnutrition before the onset of disease. Intestinal parasitism, recent migra- tion into the area, and house location within the area did not influence the progression of infection to disease. Serological testing indicated that 7.5 Vo of children were infected with Leishmania each year and that the ratio of disease to infection was 1:18.5 for the whole area and 1:6.5 for the section with the highest prevalence of disease. Early diagno- sis and therapy altered clinical patterns of the disease.
The Journal of Infectious Diseases © 1986 Oxford University Press