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Detection of Antibody to Rubella Virus by Enzyme-Linked Immunosorbent Assay

Maneth Gravell, Preston H. Dorsett, Otto Gutenson and Anita C. Ley
The Journal of Infectious Diseases
Vol. 136, Supplement. Enzymed-Linked Immunosorbent Assay (ELISA) for Infectious Agents (Oct., 1977), pp. S300-S303
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30107916
Page Count: 4
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Detection of Antibody to Rubella Virus by Enzyme-Linked Immunosorbent Assay
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Abstract

Titers of antibody to rubella virus in 68 human sera were compared by hemagglutination inhibition and enzyme-linked immunosorbent assay (ELISA). In general, the titers measured by ELISA were higher than those found by hemagglutination inhibition. Although the titers differed, the two methods showed parallel trends. Use of purified rubella virus and addition of 1% bovine serum albumin to the test wash solution aided in reducing false-positive titers in ELISA.

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