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Serotypes Responsible for Invasive Streptococcus pneumoniae Infections among Children in Connecticut
Eugene D. Shapiro and Robert Austrian
The Journal of Infectious Diseases
Vol. 169, No. 1 (Jan., 1994), pp. 212-214
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/30113210
Page Count: 3
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Active prospective surveillance to identify the serotypes of Streptococcus pneumoniae responsi-ble for invasive infections among children in Connecticut was conducted from July 1984 through March 1993. S. pneumoniae isolates (722) recovered from normally sterile sites (98% from blood, 7% from both blood and cerebrospinal fluid) were serotyped by the Quellung reaction; 70% of the isolates were from children <2 years old. Serotype 14 caused 29% of the infections. Seven serotypes (4, 6B, 9V, 14, 18C, 19F, and 23F) were responsible for 84% of the invasive infections overall and for 86% of the invasive infections among children <2 years old. Formulations of polysaccharide-protein conjugate pneumococcal vaccines designed to prevent invasive infections in children in the United States should include these commonly isolated serotypes.
The Journal of Infectious Diseases © 1994 Oxford University Press