Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Opa-Typing Can Identify Epidemiologically Distinct Subgroups within Neisseria gonorrhoeae Multi-Antigen Sequence Type (NG-MAST) Clusters

A. K. Morris, H. M. Palmer and H. Young
Epidemiology and Infection
Vol. 136, No. 3 (Mar., 2008), pp. 417-420
Stable URL: http://www.jstor.org/stable/30221491
Page Count: 4
  • Read Online (Free)
  • Download ($49.00)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Opa-Typing Can Identify Epidemiologically Distinct Subgroups within Neisseria gonorrhoeae Multi-Antigen Sequence Type (NG-MAST) Clusters
Preview not available

Abstract

A collection of 106 Neisseria gonorrhoeae ciprofloxacin-resistant isolates were typed using Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST). Opa-typing was performed on 74 isolates which had non-unique sequence types to determine if further discrimination could be achieved and if so whether this had any epidemiological basis. The 74 isolates were separated into 12 sequence types and 20 opa-types (OT). Seven opa-type clusters were congruent with the sequence types and five sequence types could be subdivided by opa-typing. These results demonstrate that opa-typing can add a further level of discrimination compared with NG-MAST. The surveillance data for isolates in the largest sequence type cluster (ST 147) indicated that two major subdivisions OT 1 and OT 2 differed epidemiologically by patients' sexual preference and geographical location. ST 147 is a common strain that has been isolated in several countries since 1999; our results suggest that it has diverged into at least two epidemiologically discrete forms.

Page Thumbnails

  • Thumbnail: Page 
[417]
    [417]
  • Thumbnail: Page 
418
    418
  • Thumbnail: Page 
419
    419
  • Thumbnail: Page 
420
    420