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Toward a Realistic Model of Mutations Affecting Fitness
Peter D. Keightley and Michael Lynch
Vol. 57, No. 3 (Mar., 2003), pp. 683-685
Published by: Society for the Study of Evolution
Stable URL: http://www.jstor.org/stable/3094781
Page Count: 3
You can always find the topics here!Topics: Genetic mutation, Genetics, Drosophila, Ecological competition, Mutagenesis, Phenotypic traits, Quantitative traits, Productivity, Statistical estimation, Viability
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Analysis of a recent mutation accumulation (MA) experiment has led to the suggestion that as many as one-half of spontaneous mutations in Arabidopsis are advantageous for fitness. We evaluate this in the light of data from other MA experiments, along with molecular evidence, that suggest the vast majority of new mutations are deleterious.
Evolution © 2003 Society for the Study of Evolution