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Adaptation of Nippostrongylus brasiliensis to the Mouse
Richard B. Wescott and A. C. Todd
The Journal of Parasitology
Vol. 52, No. 2 (Apr., 1966), pp. 233-236
Stable URL: http://www.jstor.org/stable/3276476
Page Count: 4
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Nippostrongylus brasiliensis was serially passed in mice for over 30 consecutive generations. Periodically during this work comparisons were made of the ability of the mouse-passed population and the original rat strain of the parasite to develop in both rats and mice. Mouse passage was found to significantly enhance the ability of the parasite to develop in mice after four mouse passages, and to significantly decrease the ability of the parasite to develop in rats after eight mouse passages.
The Journal of Parasitology © 1966 The American Society of Parasitologists