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Salivary Gland Antigens of Ixodes dammini Are Glycoproteins That Have Interspecies Cross-Reactivity

Christine M. Wheeler, James L. Coleman and Jorge L. Benach
The Journal of Parasitology
Vol. 77, No. 6 (Dec., 1991), pp. 965-973
DOI: 10.2307/3282751
Stable URL: http://www.jstor.org/stable/3282751
Page Count: 9
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Salivary Gland Antigens of Ixodes dammini Are Glycoproteins That Have Interspecies Cross-Reactivity
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Abstract

Serum from rabbits and rats exposed to Ixodes dammini adults and larvae, respectively, contain antibodies to a large number of antigens in salivary gland homogenates from adult ticks that cross react with the antigens of a closely related species, Ixodes scapularis, and significantly with Dermacentor variabilis antigens. The salivary gland antigens of I. dammini are glycoproteins composed of both N- and O-linked carbohydrate chains. The antigenic determinants reside in both the polypeptide and carbohydrate chains.

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