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Journal Article

Presbytis entellus, a New Experimental Host for Plasmodium fragile

S. K. Puri and G. P. Dutta
The Journal of Parasitology
Vol. 80, No. 1 (Feb., 1994), pp. 156-158
DOI: 10.2307/3283362
Stable URL: http://www.jstor.org/stable/3283362
Page Count: 3

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Topics: Infections, Parasites, Parasitemia, Parasite hosts, Malaria, Parasitology, Patents, Bonnets, Anemia, Erythrocytes
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Presbytis entellus, a New Experimental Host for Plasmodium fragile
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Abstract

The course of blood-induced Plasmodium fragile infection in 3 simian hosts, Macaca radiata (bonnet monkey), Macaca mulatta (rhesus monkey), and Presbytis entellus (Indian langur), was studied. The infection in 8 bonnet monkeys was very mild and non-fatal. In M. mulatta, P. fragile produced acute initial infection followed by anemia and death in 3 of 6 monkeys. The parasite has a relatively high level of virulence for P. entellus, a new experimental host for P. fragile, in which peak parasitemia ranging between 15 and 75% was recorded, and the infection was uniformly fatal. Plasmodium fragile infection in P. entellus can serve as an ideal biological counterpart to human Plasmodium falciparum.

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