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Anemia in Experimental Visceral Leishmaniasis in Hamsters
Tuli Biswas, Munmun Chakraborty, Khudiram Naskar, Dilip Kumar Ghosh and Jharna Ghosal
The Journal of Parasitology
Vol. 78, No. 1 (Feb., 1992), pp. 140-142
Stable URL: http://www.jstor.org/stable/3283701
Page Count: 3
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Experimental infection of hamsters with Leishmania donovani caused visceral leishmaniasis in which hematological changes occurred. The infected hamsters were anemic and reticulocyte counts were high. No significant change in the serum erythropoietin level was noted. Red cell membrane Na+-K+-ATPase and acetylcholinesterase activities increased. Osmotic fragility of the erythrocytes from infected animals increased. The level of 2,3-diphosphoglycerate of the red cells increased with the degree of anemia.
The Journal of Parasitology © 1992 The American Society of Parasitologists