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Limited Range of Genetic Variation in Echinococcus multilocularis
Heinz Rinder, Robert L. Rausch, Kenichi Takahashi, Hartmuth Kopp, Angelika Thomschke and Thomas Löscher
The Journal of Parasitology
Vol. 83, No. 6 (Dec., 1997), pp. 1045-1050
Stable URL: http://www.jstor.org/stable/3284359
Page Count: 6
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DNA sequencing of 1.3 kb of rDNA containing both internal transcribed spacers (ITS1, ITS2) and adjoining rRNA coding regions in each of 11 Echinococcus multilocularis isolates from Germany, Japan, and Alaska resulted in identical nucleotide sequences except for a single polymorphic locus 54 bp upstream of the 3' end of the 18S coding region, separating Eurasian isolates from an Alaskan isolate. The same base substitution was found in each of 2 additional isolates from Alaska. The distribution of the resulting genotypes with regard to their origin is highly significant (>99.9%) and corresponds to the traditional subspecies Echinococcus multilocularis and Echinococcus multilocularis sibiricensis.
The Journal of Parasitology © 1997 The American Society of Parasitologists