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Epidemiological Evidence of Carcinogenicity of Chlorinated Organics in Drinking Water
Kenneth P. Cantor
Environmental Health Perspectives
Vol. 46 (Dec., 1982), pp. 187-195
Published by: The National Institute of Environmental Health Sciences
Stable URL: http://www.jstor.org/stable/3429437
Page Count: 9
You can always find the topics here!Topics: Potable water, Chlorination, Chlorine, Disease risk, Bladder, Mortality, Water supply, Dosage, Epidemiologic studies, Case control studies
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Concern has recently been voiced over possible chronic toxicity associated with chlorination of public drinking water supplies in the United States. This paper reviews the available evidence and the studies underway to further evaluate hypothesized associations between cancer risk and byproducts of chlorination. Preliminary data from measures of halogenated volatiles and personal exposure histories from respondents in a large epidemiologic study of bladder cancer are presented. These data support the use in epidemiologic studies of categorical measures of exposure and suggest that results from completed case-control studies, based on death certificates, may have underestimated the true risk of exposure to chlorination by-products. The current generation of studies which use a case-control interview design offer many advantages over earlier efforts to evaluate this issue.
Environmental Health Perspectives © 1982 The National Institute of Environmental Health Sciences