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An Expanded Cohort Study of Cancer among Benzene-Exposed Workers in China
Song-Nian Yin, Richard B. Hayes, Martha S. Linet, Gui-Lan Li, Mustafa Dosemeci, Lois B. Travis, Zhi-Nan Zhang, De-Gao Li, Wong-Ho Chow, Sholom Wacholder, William J. Blot and The Benzene Study Group
Environmental Health Perspectives
Vol. 104, Supplement 6: Benzene Toxicity, Carcinogenesis, and Epidemiology (Dec., 1996), pp. 1339-1341
Published by: The National Institute of Environmental Health Sciences
Stable URL: http://www.jstor.org/stable/3433187
Page Count: 3
You can always find the topics here!Topics: Leukemia, Cohort studies, Mortality, Disease risk, Lymphoma, Lung neoplasms, Causes of death, Cancer, Aplastic anemia, Hyperlipidemias
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An expanded cohort study of 74,828 benzene-exposed and 35,805 unexposed workers were followed during 1972 to 1987, based on a previous study in 12 cities in China. A small increase was observed in total cancer mortality among benzene-exposed compared with unexposed workers (relative risk [RR] = 1.2). Statistically significant excesses were noted for leukemia (RR = 2.3), malignant lymphoma (RR = 4.5), and lung cancer (RR = 1.4). When risks were evaluated by leukemia subtype, only acute myelogenous leukemia was significantly elevated (RR = 3.1), although nonsignificant excesses were also noted for chronic myelogenous leukemia (RR = 2.6) and acute lymphocytic leukemia (RR = 2.3). A significant excess was also found for aplastic anemia.
Environmental Health Perspectives © 1996 The National Institute of Environmental Health Sciences