If you need an accessible version of this item please contact JSTOR User Support

Development of Atopy and Asthma: Candidate Environmental Influences and Important Periods of Exposure

David B. Peden
Environmental Health Perspectives
Vol. 108, Supplement 3 (Jun., 2000), pp. 475-482
DOI: 10.2307/3454539
Stable URL: http://www.jstor.org/stable/3454539
Page Count: 8
  • Download PDF
  • Cite this Item

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If you need an accessible version of this item please contact JSTOR User Support
Development of Atopy and Asthma: Candidate Environmental Influences and Important Periods of Exposure
Preview not available

Abstract

Atopy is a major risk factor for the development of asthma. Immune processes that lead to the development of antigen-specific IgE are essential to the development of atopy. This review examines the immune processes that are candidate targets for modulation by environmental agents; environmental and lifestyle factors that have been suggested as modulators of the development of atopy; and the impact of known environmental agents on atopic processes in the airway. The most important periods of immune development with regard to expression of atopy are likely during gestation and early childhood. A better understanding of which environmental agents are important, as well as the period of life during which these agents may exert an important effect, is essential to devising rational environmental avoidance strategies for at-risk populations.

Page Thumbnails

  • Thumbnail: Page 
475
    475
  • Thumbnail: Page 
476
    476
  • Thumbnail: Page 
477
    477
  • Thumbnail: Page 
478
    478
  • Thumbnail: Page 
479
    479
  • Thumbnail: Page 
480
    480
  • Thumbnail: Page 
481
    481
  • Thumbnail: Page 
482
    482