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Pyrimidine Dimer Excision and Mutation Frequency Decline

R. A. Haak and R. C. Bockrath
Radiation Research
Vol. 61, No. 1 (Jan., 1975), pp. 164-171
DOI: 10.2307/3574067
Stable URL: http://www.jstor.org/stable/3574067
Page Count: 8
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Pyrimidine Dimer Excision and Mutation Frequency Decline
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Abstract

The relationship between pyrimidine dimer excision and mutation frequency decline has been clarified by obtaining quantitative data on the rates of the two processes in a single bacterial strain. We have found (a) the loss of potential revertants to be significantly faster than the removal of thymine-containing dimers, and (b) the kinetics of dimer removal to be similar whether the postirradiation environment is conducive to mutation frequency decline or not.

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