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Peripheral Lymphocyte Response to PHA and T Cell Population among Atomic Bomb Survivors

Mitoshi Akiyama, Michio Yamakido, Kyoko Kobuke, Donald S. Dock, Howard B. Hamilton, Akio A. Awa and Hiroo Kato
Radiation Research
Vol. 93, No. 3 (Mar., 1983), pp. 572-580
DOI: 10.2307/3576036
Stable URL: http://www.jstor.org/stable/3576036
Page Count: 9
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Peripheral Lymphocyte Response to PHA and T Cell Population among Atomic Bomb Survivors
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Abstract

The percentage of T lymphocytes of atomic bomb survivors showed no change as a function of age or exposure dose. The percentage of T cells was slightly lower in malignant-tumor patients than in the control group, but was significantly higher in the group with chromosomal aberrations than in the control group. The percentages of phytohemagglutinin (PHA)-induced transformation of peripheral lymphocytes decreased significantly with age in the 0 rad control group and the 200+ rad exposure group, particularly so in the latter. The malignant-tumor group also showed lower percentages of PHA-induced transformation than the control group. The percentages of PHA-induced transformation of lymphocytes of the chromosomal-aberration group were significantly depressed as compared with that of the control group.

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