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Cell Survival and Plating Efficiency
D. J. Brenner, M. Zaider, C. R. Geard and M. A. Georgsson
Vol. 111, No. 3 (Sep., 1987), pp. 572-576
Published by: Radiation Research Society
Stable URL: http://www.jstor.org/stable/3576941
Page Count: 5
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The question of whether cellular radiation sensitivity is independent or related to plating efficiency (PE) is addressed. Three different cell lines, one human and mortal (AG 1522), one rodent and immortal (CHO AA8), and one rodent and mortal (C3H 10T 1/2), were investigated. The first two showed a strong correlation between radiation sensitivity and PE, even when, for the mortal cells, the effect of passage number was factored out.
Radiation Research © 1987 Radiation Research Society