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Moderate Hyperthermia and Low Dose Rate Irradiation

C. Clifton Ling and Elizabeth Robinson
Radiation Research
Vol. 114, No. 2 (May, 1988), pp. 379-384
DOI: 10.2307/3577232
Stable URL: http://www.jstor.org/stable/3577232
Page Count: 6
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Moderate Hyperthermia and Low Dose Rate Irradiation
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Abstract

Moderate hyperthermia (4 h at 40°C) enhances V-79 cell radiosensitivity at low irradiation dose rates with a maximum thermal enhancement ratio (TER) of 1.38. In comparison, the TER measured at acute dose rate is 1.13. Heat treatments given before and during irradiation are equally effective, and more so than postirradiation hyperthermia. Hyperthermia-induced inhibition of sublethal damage repair is a probable cause of the observed effect.

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