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Evaluation of U-5897 as a Male Chemosterilant for Rat Control
Alan M. Bowerman and Joe E. Brooks
The Journal of Wildlife Management
Vol. 35, No. 4 (Oct., 1971), pp. 618-624
Stable URL: http://www.jstor.org/stable/3799765
Page Count: 7
You can always find the topics here!Topics: Rats, Female animals, Testes, Lesions, Reproductive sterilization, Breeding, Reproduction, Rodents, Pregnancy, Simulations
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Laboratory studies conducted with U-5897 (3-chloro-1,2-propanediol) in individually caged and penned colonies of wild Norway rats (Rattus norvegicus) demonstrated that an effective sterilizing dose of 175 mg/kg of body weight was voluntarily consumed by 70 to 80 percent of the test males. Two similar rat-infested dumps, one serving as a control and the other as the treated site, were utilized for a field trial of U-5897 during the late summer-early fall breeding peak. After several nights of prebaiting the test site with plain bait, rats consumed 3,255 grams of the one percent U-5897 bait on the 1 night of exposure. A second application of U-5897 bait was made 11 weeks after the first, and 2,630 grams of bait was consumed in 1 night. Two weeks after the first treatment, 18 of 23 mature males exhibited effects of U-5897. A maximum of 36 percent of the mature males trapped from the test site 4, 8, and 15-17 weeks after the first treatment were sterile. During the test period, 46 of 84 mature females captured from the treated dump were either pregnant or lactating, and 34 of 73 from the control dump were pregnant or lactating. These data indicate that pregnancies and lactation were not inhibited by the level of male sterility achieved during the field trial.
The Journal of Wildlife Management © 1971 Wiley