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Journal Article

A Note on the Safety Testing of Vaccines

P. Armitage
The Journal of Hygiene
Vol. 69, No. 1 (Mar., 1971), pp. 95-97
Stable URL: http://www.jstor.org/stable/3861265
Page Count: 3

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Topics: Dosage, Vaccination, Particle density
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A Note on the Safety Testing of Vaccines
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Abstract

The use of the hypergeometric distribution in calculations of sample volumes for safety testing is criticized. Alternative interpretations of the concept of 'infective ml. doses' lead to slightly different solutions, the simplest of which, involving the exponential function, is recommended for general use.

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