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Influence of Bacterial Resistances on the Efficiency of Antibiotic Treatments for Community-Acquired Pneumonia

Ramon Sabes-Figuera, José Luis Segú, Jaume Puig-Junoy and Antoni Torres
The European Journal of Health Economics
Vol. 9, No. 1 (Feb., 2008), pp. 23-32
Published by: Springer
Stable URL: http://www.jstor.org/stable/40283693
Page Count: 10
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Influence of Bacterial Resistances on the Efficiency of Antibiotic Treatments for Community-Acquired Pneumonia
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Abstract

The objective of this paper is to perform a cost-effectiveness analysis of the oral antibiotics used in Spain for the ambulatory treatment of communityacquired pneumonia. Our analysis takes into account the influence of bacterial resistances on the costeffectiveness ratio of antibiotic alternatives from the viewpoint of the public insurer. A deterministic decision analysis model is used to simulate the impact of treatment alternatives on both patients' health and resource consumption. Amoxicillin 1 g may be the most efficient therapy for treating typical pneumonia, as long as the physician is able to discriminate clinically the aetiology of the process with a high degree of reliability. However, for those pathological pictures in which the aetiology cannot be discriminated clinically, and for those in which the consequences of incorrect diagnosis are serious according to clinical criteria, moxifloxacin is the most effective and efficient option.

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