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Persistence of Vaccinia at the Site of Smallpox Vaccination

James F. Cummings, Mark E. Polhemus, Clifton Hawkes, Mary Klote, George V. Ludwìg and Glenn Wortmann
Clinical Infectious Diseases
Vol. 46, No. 1 (Jan. 1, 2008), pp. 101-102
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/40306845
Page Count: 2
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Abstract

Persistence of vaccinia at vaccination sites may help determine the risk associated with secondary transmission. Culture, PCR, and antigen detection were performed on serial vaccination site swab specimens. On day 21 after vaccination, 37% of volunteers were culture positive, most of whom had received vaccine for the first time. Vaccinia is detectable at least through day 21 after vaccination.

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