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Treatment Responses in Antiretroviral Treatment-Naive Premenopausal and Postmenopausal HIV-1-Infected Women: An Analysis from AIDS Clinical Trials Group Studies

Kristine B. Patterson, Susan E. Conn, Jennifer Uyanik, Michael Hughes, Marlene Smurzynski and Joseph J. Eron
Clinical Infectious Diseases
Vol. 49, No. 3 (Aug. 1, 2009), pp. 473-476
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/40308715
Page Count: 4
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Treatment Responses in Antiretroviral Treatment-Naive Premenopausal and Postmenopausal HIV-1-Infected Women: An Analysis from AIDS Clinical Trials Group Studies
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Abstract

Menopause may affect antiretroviral treatment (ART) response. Immunologic and virologic responses to ART were compared in 220 premenopausal and 47 postmenopausal women enrolled in 2 studies involving ART-naive persons. Changes in CD4 counts or human immunodeficiency virus type 1 RNA levels were similar at 24, 48, and 96 weeks after treatment initiation. ART-naive women should respond to ART regardless of menopausal status.

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