Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Prevalence of Hepatitis C Virus Infection in Patients with COPD

D. R. Silva, J. Stifft, H. Cheinquer and M. M. Knorst
Epidemiology and Infection
Vol. 138, No. 2 (Feb., 2010), pp. 167-173
Stable URL: http://www.jstor.org/stable/40390543
Page Count: 7
  • Read Online (Free)
  • Download ($49.00)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Prevalence of Hepatitis C Virus Infection in Patients with COPD
Preview not available

Abstract

Some studies have suggested that chronic hepatitis C virus (HCV) infection may induce an accelerated decline of forced expiratory volume in 1 second $FEV_1 $ . We performed a cross-sectional study to determine the prevalence of HCV infection in a sample of chronic obstructive pulmonary disease (COPD) patients and in a control group of blood donors. The clinical characteristics of HCV-positive and HCV-negative patients were compared. Anti-HCV antibody was determined and confirmed by HCV-RNA. The prevalence of HCV infection in COPD patients was 7·5% (95% CI 6·52-8·48) and in blood donors was 0·41% (95% CI 0·40-0·42). The HCV-positive patients had a lower $FEV_1 $ (34·7±8·6%) and a higher BODE index (median=6) than HCV-negative patients (42·7±16·5%, median=4, respectively) (P= 0·011 and 0·027, respectively). Our results suggest a high prevalence of chronic HCV infection in patients with COPD in comparison with the blood donors. HCV-positive patients have a more severe disease.

Page Thumbnails

  • Thumbnail: Page 
[167]
    [167]
  • Thumbnail: Page 
168
    168
  • Thumbnail: Page 
169
    169
  • Thumbnail: Page 
170
    170
  • Thumbnail: Page 
171
    171
  • Thumbnail: Page 
172
    172
  • Thumbnail: Page 
173
    173