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Genes for Psychosis and Creativity: A Promoter Polymorphism of the Neuregulin 1 Gene Is Related to Creativity in People With High Intellectual Achievement
Vol. 20, No. 9 (September 2009), pp. 1070-1073
Stable URL: http://www.jstor.org/stable/40575144
Page Count: 4
You can always find the topics here!Topics: Creativity, Neuregulins, Genotypes, Questionnaires, Socioeconomic status, Creativity tests, Originality, Schizophrenia, Genes, Genetics
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Why are genetic polymorphisms related to severe mental disorders retained in the gene pool of a population? A possible answer is that these genetic variations may have a positive impact on psychological functions. Here, I show that a biologically relevant polymorphism of the promoter region of the neuregulin 1 gene (SNP8NRG243177lrs6994992) is associated with creativity in people with high intellectual and academic performance.Intriguingly, the highest creative achievements and creative-thinking scores were found in people who carried the T/T genotype, which was previously shown to be related to psychosis risk and altered prefrontal activation.
Psychological Science © 2009 Association for Psychological Science