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MSAFP Levels in Aboriginal Canadian Women

B.N. Chodirker, L.B. Erdile, K.M. MacDonald, C.R. Harman, M.S. Cheang and J.A. Evans
Canadian Journal of Public Health / Revue Canadienne de Santé Publique
Vol. 85, No. 6 (NOVEMBER / DECEMBER 1994), pp. 424-426
Stable URL: http://www.jstor.org/stable/41991224
Page Count: 3
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Abstract

Maternal serum alpha-fetoprotein (MSAFP) levels in 529 non-diabetic aboriginal Canadian women were compared with levels in 13,285 non-diabetic non-aboriginal women. A woman was considered to be aboriginal if she was listed on the Indian Register of Canada. After controlling for the gestational age on the date at which the sample was drawn and maternal weight, MSAFP levels appeared to be approximately 4 to 5% higher in aboriginal women. The possible implications of this finding on an MSAFP screening program are discussed. Les concentrations sériques d'alpha fétoprotéines de 529 femmes autochtones ont été comparées à celles de 13 285 canadiennes. Après qu'on eut ajusté pour l'âge de la gestation et le poids de la mère au moment où les prélèvements ont été collectés, on a trouvé que les concentrations des femmes autochtones étaient de 4 à 5 % plus élevées. Les implications de cette observation pour le dépistage des alpha fétoprotéines sont discutées.

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