You are not currently logged in.
Access JSTOR through your library or other institution:
If You Use a Screen ReaderThis content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Lymphoid Cell Line Identification and the Detection of Cross Contamination
Betty R. Conner, Soldano Ferrone, Michele A. Pellegrino and Ronald Glaser
Vol. 16, No. 5 (May, 1980), pp. 446-452
Published by: Society for In Vitro Biology
Stable URL: http://www.jstor.org/stable/4292362
Page Count: 7
You can always find the topics here!Topics: Cell lines, Lymphocytes, Tumor cell line, Antigens, Epstein Barr virus infections, Burkitt lymphoma, HLA A antigens, Cultured cells, Chromosomes, Tumors
Were these topics helpful?See somethings inaccurate? Let us know!
Select the topics that are inaccurate.
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Preview not available
Four lymphoid cell lines, presumably recent derivatives from non-neoplastic human tonsils, were identified in actuality as established Burkitt lymphoma and lymphoblastoid cell lines (LCL) when tested by chromosome banding and typing for HLA antigens. Additionally, the morphology, growth characteristics, tumorigenicity, expression of Epstein-Barr virus antigens and surface membrane immunoglobulins (SmIg) of the four lymphoid cell lines confirmed the correct identifications. In determining the possibility of cross contamination, the most reliable criteria for the identification of lymphoid cell lines were found to be HLA antigenic profile, karyotype, cellular morphology, and growth characteristics.
In Vitro © 1980 Society for In Vitro Biology