You are not currently logged in.
Access your personal account or get JSTOR access through your library or other institution:
Pathogenicity of Anaerobic Gram-Negative Rods: Possible Mechanisms
Reviews of Infectious Diseases
Vol. 6, No. 2 (Mar. - Apr., 1984), pp. 189-199
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/4453280
Page Count: 11
Preview not available
The literature dealing with the pathogenicity of anaerobic gram-negative rods in humans is reviewed. Knowledge concerning definite pathogenic mechanisms is, at best, cursory. There is evidence that encapsulation plays a role in the pathogenicity of Bacteroides fragilis and some of the black-pigmented Bacteroides. A range of enzymes, among them collagenase and IgA protease, are produced by several Bacteroides species. Supernatants of Fusobacterium necrophorum cultures may be leukotoxic. The cell wall lipopolysaccharides of Fusobacterium species are powerful endotoxins. Synergism between anaerobic gram-negative rods and other bacterial species has been demonstrated in experimental animals.
Reviews of Infectious Diseases © 1984 Oxford University Press