You are not currently logged in.
Access JSTOR through your library or other institution:
Bacteremic Disease Due to Haemophilus influenzae Capsular Type f in Adults: Report of Five Cases and Review
Leonard N. Slater, Joseph Guarnaccia, Sue Makintubee and Gregory R. Istre
Reviews of Infectious Diseases
Vol. 12, No. 4 (Jul. - Aug., 1990), pp. 628-635
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/4455602
Page Count: 8
Preview not available
Five cases of bacteremic infections due to Haemophilus influenzae type f in adults are described, and previous reports of type f disease in nonpediatric patients are reviewed. Respiratory tract infections were most common in our series (two cases of pneumonia, one of epiglottitis, and one of nosocomial septicemia probably resulting from aspiration pneumonitis). All of these patients had factors predisposing them to respiratory tract infections, e.g., neurologic disease, congestive heart failure, or cigarette smoking. A fifth patient, who was bacteremic without an apparent primary focus, had dysgammaglobulinemia. Six episodes of bacteremia occurred in five patients; 11 of 13 cultures of blood obtained before parenteral antibiotic therapy were positive. All isolates were biotype I and susceptible to ampicillin. Antibiotic therapy was curative in cases of proved respiratory tract infection but failed in the setting of nosocomial septicemia, perhaps because of delayed initiation. The brevity of antibiotic treatment of the cryptogenic bacteremia permitted infection of a prosthetic vascular graft and recurrent bacteremia. Graft removal and repeated antibiotic therapy were curative.
Reviews of Infectious Diseases © 1990 Oxford University Press