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Validation of a Screening Instrument to Identify Persons for Exclusion from Smallpox Vaccination

Edward A. Belongia, Allison Naleway, Burney Kieke, Salah Qutaishat, Christine Casey, David K. Shay and Robert T. Chen
Clinical Infectious Diseases
Vol. 40, No. 4 (Feb. 15, 2005), pp. 620-623
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/4463079
Page Count: 4
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Validation of a Screening Instrument to Identify Persons for Exclusion from Smallpox Vaccination
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Abstract

Adults must be screened for atopic dermatitis and other contraindications before smallpox vaccination. We validated the sensitivity of a self-administered Centers for Disease Control and Prevention (Atlanta, GA) screening questionnaire completed by 174 hospital workers, with the workers' medical records as the reference standard. The questionnaire failed to identify one-third of the subjects who had a contraindication, although the incidence of serious adverse events has been low among vaccinees. Further assessment of screening procedures is needed if the administration of smallpox vaccine becomes more widespread in the future.

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